Episode 1: Dying Changes Everything: House's preoccupation with Wilson leaves his team without direction and endangers the patient, a female whose exhaustive work schedule and demanding boss may have caused her condition.
Episode 2: Not Cancer: Years after receiving body parts from the same organ donor, five out of six recipients die within a few months. House and the team race against time to figure out why before the final surviving recipient, a young woman who received the donor's cornea, dies as well. Meanwhile House hires a private detective to investigate patients, doctors and his estranged friend, Wilson.
Episode 3: Adverse Events: House uses his investigator's information to stir a few pots. Meanwhile the team tries to cure a portrait artist with a vision problem.
Episode 4: Birthmarks: House tries every delaying tactic available when Wilson forces him to attend his father's funeral. Meanwhile, the team tries to find the cause of a young woman's abdominal pain and haemorrhaging.